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Description

20 , e54e64 (2019)

These mutations are referred to as CRIM-negative mutations where CRIM means cross-reactive immunologic material. Type I mutations represent the largest percentage of mutations in AIP patients, consisting of approximately 85% of mutations

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Rather than being investigated within a single biological pathway, it has featured in laboratory studies examining molecular signalling, extracellular matrix biology and the complex interactions that influence normal tissue organisation